Arsene Wenger is feeling the pressure and desperately needs a win over Manchester United to ease the criticism he has been facing.
Arsenal might be within touching distance of the Premier League's summit, but their embarrassing Champions League loss to Olympiacos during the week has ramped up the pressure on their stars.
Life is a little simpler for United. A win in midweek aided their European ambitions while they were sitting pretty at the top of the table before Manchester City regained top spot yesterday.
Clashes between these two old rivals have a history of being feisty and fierce affairs - and this one will surely be no different as both teams deal with their fans' big expectations.
Here is all you need to know...
1. When is the match and where can I see it?
United's trip to Arsenal will kick-off at 4:00pm on Sunday afternoon.
Those wanting to watch the match should tune into Sky Sports 1 following the conclusion of the Everton vs Liverpool match.
2. Team news
Arsenal: OUT - Koscielny (hamstring), Arteta (thigh), Flamini (hamstring), Wilshere (leg), Rosicky (knee), Welbeck (knee).
Man United: OUT - Rojo (hamstring), Shaw (leg). DOUBTFUL - Carrick (knock), Herrera (knock).
3. Predicted sides
Arsenal:
Man United:
4. Reasons for Arsenal fans to be optimistic
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Theo Walcott is in fine form, netting six goals in seven appearances for club and country.
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Alexis Sanchez ended his Premier League goal drought last weekend, plundering a hat-trick against Leicester.
5. Reasons for Man United fans to be optimistic
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United haven't lost at the Emirates in any of their last four Premier League encounters there, winning two and drawing two.
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The Red Devils have suffered defeat in just three of their last 21 clashes with Arsenal in all competitions.
6. Recent meetings
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Manchester United 1-1 Arsenal (May 2015)
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Manchester United 1-2 Arsenal - FA Cup (March 2015)
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Arsenal 1-2 Manchester United (November 2014)
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Arsenal 0-0 Manchester United (February 2014)
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Manchester United 1-0 Arsenal (November 2014)
7. Recent form
Arsenal - Last 5 games
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Arsenal 2-3 Olympiakos (Champions League)
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Leicester City 2-5 Arsenal (Premier League)
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Tottenham 1-2 Arsenal (Capital One Cup)
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Chelsea 2-0 Arsenal (Premier League)
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Dinamo Zagreb 2-1 Arsenal (Champions League)
Manchester United - Last 5 games
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Manchester United 2-1 Wolfsburg (Champions League)
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Manchester United 3-0 Sunderland (Premier League)
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Manchester United 3-0 Ipswich Town (Capital One Cup)
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Southampton 2-3 Manchester United (Premier League)
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PSV Eindhoven 2-1 Manchester United (Champions League)
Source: Mirror.co.uk